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Why sertraline and sibutramine interact with each other?

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suzanne66 8 Sep 2010

The combination of Sertraline and Sibutramine should be avoided because of the risk of developing a rare but serious, potentially life threatening, condition called "serotonin syndrome".
This condition is bought about because of over-stimulation of particular serotonin receptors in the brain.
See: https://www.drugs.com/drug-interactions/sibutramine-with-zoloft-2060-0-2057-1348.html

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