... months it has been making me violently vomit. Why?? I noticed that for the last 2 months my oxycontin is very different in size and color. Now I am taking only the percocet that I used for breakthrough pain. I am a cronic pain suffer. The oxycontin along with the percocet was giving me relief. Now I am constsntly in severe pain. HELP!!
Why is 0xycontin making me sick? I've been taking oxyc0ntin for 10 years but for the last two?
- Asked
- 17 Nov 2010 by kATE1946
- Updated
- 21 Nov 2016
- Topics
- oxycontin, percocet, pain
Responses (4)
It sounds as if you take the OP version which was manufactured differently to prevent abuse. Many people (the vast majority so far here on DC) Have had complaints. It doesn't work as well for pain and some meds pass right through with out even dissolving.
I will post Purdues Official Statement regarding the new ocycontin, now OP.I would urge you to contact the reps listed and log your complaint.
best wishes and feel better soon.
chris
Thanks UNLVGRAD, always follow up on other possibilities! Hope you've been doing ok lately? It sure is a tough world out there.
Be safe too,
chris
I almost died because I take OxyContin for chronic pain from a rare neurological illness ( had brain surgery) no one told me I could not take xanax as well. I was found unresponsive by my aid, a health worker, in my living room floor I spent over 3 weeks in the hospital when I came to I could barely talk hardly knew anything about myself I could not walk I was in really bad shape. Both of these meds were prescribed for me yet, neither my dr or the pharmacy told me what a danger it was to me. I'm so angry! I only want to say be very careful when taking this medicine please. There are many meds you can't take while taking it and it can be deadly if you take them. Read everything you can about it Inform yourself as much as you can. God bless you all and I hope you feel better and will not need to use any pain med .

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Details:
The new OP (all strengths) will be replacing the regular OC version by the end of 2010. Many people are having problems with this new medication. Here is Purdue's official statement and the reps you can contact with any concerns/complaints, or questions you may have.
James Heins
(203) 588-8069 (office)
(203) 856-2121 (mobile)
email James.Heins@pharma.com
OR
Libby Holman
(203) 856-7670 (office)
(203) 609-1291 (mobile)
email Libby.Holman@pharma.com
OFFICIAL STATEMENT:
April 5, 2010 - The U.S. Food and Drug Administration (FDA) approved Purdue Pharma L.P.'s New Drug Application for a reformulation of OxyContin® (oxycodone HCl controlled-release) Tablets.
The reformulation has met FDA criteria for bioequivalence to the original formulation, which means there is no significant difference in the rate and extent of absorption of the therapeutic ingredient.
Expand...
While similar in appearance to the original formulation, the reformulated tablets have a different marking ("OP") than the currently marketed tablets (marking "OC") and the 60 mg and 80 mg tablets are slightly larger in size than the currently marketed tablets.
Purdue elected to reformulate OxyContin® to be bioequivalent to the original formulation and in an effort to make the tablet more difficult to manipulate for the purpose of intentional misuse and abuse, however, there is no evidence that the reformulation of OxyContin is less subject to misuse, abuse, diversion, overdose or addiction.
OxyContin® continues to be a CII controlled substance with all the attendant risks of Schedule II opioids, specifically that the drug has a high potential for abuse. Use, misuse, or abuse of the drug may lead to physical dependence or addiction (addiction is sometimes referred to as "psychological dependence"). In addition, alteration of the tablet in any manner poses significant risks of overdose and death. The Full Prescribing Information contains warnings about the potential for abuse, diversion, overdose and addiction, including a boxed warning (see below).
Indications and Usage
OxyContin® is a controlled-release oral formulation of oxycodone hydrochloride indicated for the management of moderate to severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time.
Limitations of Usage
OxyContin® is not intended for use on an as-needed basis.
As used here, "moderate" and "moderate to severe" pain do not include commonplace and ordinary aches and pains, pulled muscles, cramps, sprains, or similar discomfort.
OxyContin® is not indicated for the management of pain in the immediate postoperative period (the first 12-24 hours following surgery), or if the pain is mild, or not expected to persist for an extended period of time. OxyContin® is indicated for postoperative use following the immediate post-operative period only if the patient is already receiving the drug prior to surgery or if the postoperative pain is expected to be moderate to severe and persist for an extended period of time. Physicians should individualize treatment, moving from parenteral to oral analgesics as appropriate. (See American Pain Society guidelines.)
OxyContin® is not indicated for pre-emptive analgesia (preoperative administration for the management of postoperative pain).
OxyContin® is not indicated for rectal administration.
Important Safety Information
OxyContin® is contraindicated in patients who have significant respiratory depression, patients who have or are suspected of having paralytic ileus, patients who have acute or severe bronchial asthma, and patients who have known hypersensitivity to any of its components or the active ingredient, oxycodone.
Opioid analgesics have a narrow therapeutic index in certain patient populations, especially when combined with CNS depressant drugs, and should be reserved for cases where the benefits of opioid analgesia outweigh the known risks of respiratory depression, altered mental state, and postural hypotension. Use low initial doses of OxyContin® in patients who are not already opioid-tolerant, especially those who are receiving concurrent treatment with muscle relaxants, sedatives, or other CNS active medications.
Serious adverse reactions which may be associated with OxyContin® Tablet therapy in clinical use are respiratory depression, apnea, respiratory arrest, and circulatory depression, hypotension, or shock. The most common adverse reactions (>5%) include: constipation, nausea, somnolence, dizziness, vomiting, pruritus, headache, dry mouth, asthenia, and sweating.
REMS
Working with the FDA, Purdue has developed a Risk Evaluation and Mitigation Strategy (REMS) for OxyContin® Tablets. The OxyContin REMS includes a Medication Guide, Elements to Assure Safe Use, such as healthcare provider training and a timetable for submitting assessments of the REMS.
Product Shipment
The Company expects to begin shipping all dosage strengths of the reformulated product (10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg and 80 mg) to distributors and pharmacies during the third quarter of 2010, at which time Purdue will cease shipping the original formulation.
"We will work with distributors and pharmacies for a smooth transition to the reformulation that will maintain product supply and protect patient access," said John H. Stewart, President and CEO of Purdue Pharma L.P.
https://www.drugs.com/answers/purdue-pharma-official-statement-re-new-op-323421.html
Great info chris!!