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Why heparin induce osteoprosis?

Responses (1)

Rajive Goel 5 May 2010

Perhaps due to long-term heparin treatment causes osteoporosis through an as not well defined mechanism. In a work published in 1996 one can notice that biochemical markers of bone turnover showed that heparin treatment produced a dose-dependent decrease in serum alkaline phosphatase and a transient increase in urinary PYD thus confirming the decreasing in trabecular bone volume of histomorphometric data: heparin decreases the rate of bone formation and increases the rate of bone resorption, hope this is of help?

ruaa aqtash 5 May 2010

thanks alot

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