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Why caffeine increase the absorption of ergotamine?

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suzanne66 26 May 2010

Caffeine increases both the rate and extent of absorption of ergotamine when given together.
Caffeine is thought to exert its rate-accelerating effect by increasing the water solubility of ergotamine - thereby assisting ergotamine absorption from a lipid phase (GI membrane) into an aqueous phase (blood). free discount card

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