... The reason I ask is that my husband recently started taking Synthroid at 25 mcg and recently had it adjusted to 50 mcg for the next 6 weeks.
He has experienced feeling a bit lightheaded, mild headache, less tiredness in the morning (but not through out the rest of the day), lessening of anxiety/depression symptoms and more over-all motivation.

Still, as of the last blood test his levels aren't where they're supposed to be and he's a bit concerned about what to expect in the meantime between being dx with hypothyroidism and then getting to the point where the hormone supplement is at the right dosage. Is there a certain way he will be able to tell that he's better?