Well all narcotics have metabolites which can cause harm in negative ways, such as addiction, and they can cause withdrawal symptoms if the narcotic not taken. They all have metabolites which can cause harm if too much of the drug is taken.
I don't know of one particular narcotic which has an extremely dangerous metabolite which can cause harm if the drug is taken at a regular dose, long term.
Please try the forum. Someone may be able to give more information.
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