I have asked many Doctors About this--- I am 50, and have normal blood pressure,however I have BPH. I go To the washroom ever 60-75 minutes,I drive a bus for a living.It is difficult at times. I also may have inflammation of the prostate do to sitting and certain foods and coffee.However I still think Ramipril has something to do with it. Can You Help???
I have found that Ramipril can cause a decrease of output urine.
I also found this:
"Cardiovascular: Symptomatic hypotension (reported in 0.5% of patients in US trials), syncope and palpitations.
Hematologic: Pancytopenia, hemolytic anemia and thrombocytopenia.
Renal: Some hypertensive patients with no apparent preexisting renal disease have developed minor, usually transient, increases in blood urea nitrogen and serum creatinine when taking Ramipril, particularly when Ramipril was given concomitantly with a diuretic. Acute renal failure.
Angioneurotic Edema: Angioneurotic edema has been reported in 0.3% of patients in US clinical trials.
Gastrointestinal: Hepatic failure, hepatitis, jaundice, pancreatitis, abdominal pain (sometimes with enzyme changes suggesting pancreatitis), anorexia, constipation, diarrhea, dry mouth, dyspepsia, dysphagia, gastroenteritis, increased salivation and taste disturbance.
Dermatologic: Apparent hypersensitivity reactions (manifested by urticaria, pruritus, or rash, with or without fever), photosensitivity, purpura, onycholysis, pemphigus, pemphigoid, erythema multiforme, toxic epidermal necrolysis, and StevensJohnson syndrome.
Neurologic and Psychiatric: Anxiety, amnesia, convulsions, depression, hearing loss, insomnia, nervousness, neuralgia, neuropathy, paresthesia, somnolence, tinnitus, tremor, vertigo, and vision disturbances.
Miscellaneous: As with other ACE inhibitors, a symptom complex has been reported which may include a positive ANA, an elevated erythrocyte sedimentation rate, arthralgia/arthritis, myalgia, fever, vasculitis, eosinophilia, photosensitivity, rash and other dermatologic manifestations. Additionally, as with other ACE inhibitors, eosinophilic pneumonitis has been reported.
Fetal/Neonatal Morbidity and Mortality. See WARNINGS: Fetal/Neonatal Morbidity and Mortality.
Other: Arthralgia, arthritis, dyspnea, edema, epistaxis, impotence, increased sweating, malaise, myalgia, and weight gain.
In addition to adverse events reported from clinical trials, there have been rare reports of hypoglycemia reported during Ramipril therapy when given to patients concomitantly taking oral hypoglycemia agents or insulin. The causal relationship is unknown.
Clinical Laboratory Test Findings
Creatinine and Blood Urea Nitrogen: Increases in creatinine levels occurred in 1.2% of patients receiving Ramipril alone, and in 1.5% of patients receiving Ramipril and a diuretic. Increases in blood urea nitrogen levels occurred in 0.5% of patients receiving Ramipril alone and in 3% of patients receiving Ramipril with a diuretic. None of these increases required discontinuation of treatment. Increases in these laboratory values are more likely to occur in patients with renal insufficiency or those pretreated with a diuretic and, based on experience with other ACE inhibitors, would be expected to be especially likely in patients with renal artery stenosis. Since Ramipril decreases aldosterone secretion, elevation of serum potassium can occur. Potassium supplements and potassiumsparing diuretics should be given with caution, and the patient's serum potassium should be monitored frequently.
Hemoglobin and Hematocrit: Decreases in hemoglobin or hematocrit (a low value and a decrease of 5 g/dL or 5% respectively) were rare, occurring in 0.4% of patients receiving Ramipril alone and in 1.5% of patients receiving Ramipril plus a diuretic. No US patients discontinued treatment because of decreases in hemoglobin or hematocrit.
Other (causal relationships unknown): Clinically important changes in standard laboratory tests were rarely associated with Ramipril administration. Elevations of liver enzymes, serum bilirubin, uric acid, and blood glucose have been reported, as have cases of hyponatremia and scattered incidents of leukopenia, eosinophilia, and proteinuria. In US trials, less than 0.2% of patients discontinued treatment for laboratory abnormalities; all of these were cases of proteinuria or abnormal liverfunction tests."
I am more apt believe that this is a case of sitting too much.
- Ramipril Information for Consumers
- Ramipril Information for Healthcare Professionals (includes dosage details)
- Side Effects of Ramipril (detailed)
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