Both Amaryl and Prandin are used to treat Type 2 diabetes.
They lower blood sugar by causing the pancreas to produce insulin.
Amaryl (glimepiride) belongs to the class of drugs called sulfonylureas.
Prandin (repaglinide) belongs to the newer family of drugs called "meglitinides"
Sulfonylurea drugs stimulate insulin production for 8-12 hours regardless of blood sugar level. They are usually given once daily. Hypoglycaemia can be a problem with these drugs.
Unlike the sulfonylureas the meglitinides are very short acting, with peak effects within one hour. For this reason, they are given up to three times a day just before meals. Hypoglycemia is less frequent than seen with sulfonylureas.
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