My 17mth old has been on 9mg lansoprazole daily for severe GERD since he was 8mth. He is now 17mth and weighs 22lb. His GERD is under control, but he is anaemic and suffering from poor weight gain. He continues to have problems with gastrointestinal pain, constipation (for which he has movicol paed) and gastrointestinal dysmotility. Could the lansoprazole long term be contributing to any of this, particularly the absorbtion of iron, and should it be discontinued? He is thought to have segmental NF1, is it more likely that the NF1 is causing his problems?