I am thinking about 20 minutes to reach peak effectiveness and, since I am prescribed a dose three times per day, that it should be effective for 8 hours. Is there a web site that has graphs showing this information for all drugs?
monster0411, I take hydrocodone10/325 myself & have learned a little trick that helps me get a quicker reaction time. Don't know why this works, but seems to everytime. I am on a 4 hourly dose right now becaue of surgery, but maintain a usual dose of every six hours. I take mine on an empty stomach; wait about 15 minutes, & then eat something! Whether it be a few crackers or a cookie or dinner it doesn't matter. It seems letting the drug disolve on my empty stomach & then filling it up gets it to kick in fast! Don't know if that works for anyone else, but when I'm jonesing for that next dose because my pain is so bad, it really works. Hope this helps you out...
The onset has to do with the peak time to reach maximum blood level which for hydrocodone with ibuprofen is approximately 1.7 to 1.8 hours. The effective duration has to do with the elimination half life which is 4.5 hours and a plasma half life of 2.2 hours so it remains effective for 4 to 6 hours after taking the dose. You can read about the pharmokenitics of this drug at the following website:
Hope this helps,
- Hydrocodone / Ibuprofen Information for Consumers
- Hydrocodone / Ibuprofen Information for Healthcare Professionals (includes dosage details)
- Side Effects of Hydrocodone / Ibuprofen (detailed)
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