Have mvp with mildly moderate regurgitation. In past I have had episodes of pvcs and multi-focal auricular tachcardia. One of my sons has had tachycardia from childhood and one of my daughters has mitral valve. From time to time I have experimented with taking medication at different times of the day, but was just wondering about others' experience, and if there were a "best" time of day for my particular problem to take it.