What is the suitable dose for an eighty year old patient?should it be a 5mg daily or 10mg?
Vesicare (solifenacin) reduces muscle spasms of the bladder and urinary tract.
Vesicare is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage). The dosage recommendations at the bottom are just a guideline but you need to follow your doctors instructions as doses may be adjusted depending on other co-morbidities the patient has.
Dosage and Administration for VESIcare
The recommended dose of VESIcare is 5 mg once daily. If the 5 mg dose is well tolerated, the dose may be increased to 10 mg once daily.
VESIcare should be taken with liquids and swallowed whole. VESIcare can be administered with or without food.
Dose Adjustment in Renal Impairment
For patients with severe renal impairment (CLcr <30 mL/min), a daily dose of VESIcare greater than 5 mg is not recommended.
Dose Adjustment in Hepatic Impairment
For patients with moderate hepatic impairment (Child-Pugh B), a daily dose of VESIcare greater than 5 mg is not recommended. Use of VESIcare in patients with severe hepatic impairment (Child-Pugh C) is not recommended.
Dose Adjustment CYP3A4 Inhibitors
When administered with therapeutic doses of ketoconazole or other potent CYP3A4 inhibitors, a daily dose of VESIcare greater than 5 mg is not recommended.
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