After 20 years of taking all approved SSRIs, SSNRs, and tricyclic antidepressants, my doctor has prescribed Parnate. I am currently taking 60 mg/day, and I have noticed some improvement, but not significant. I read an article that some patients require 90+mg/day to achieve efficacy. One reviewer below noted 160 mg/day of Parnate as his/her effective dose. All input is appreciated.
Hello amybethcaruso. I was on Parnate, back in 1995. It was short lived in as much as I didn't respond to it and then I went the route of ect. I believe my dose ended being 90mg. It really does vary from one person to another, the severity of the depression. I truly hope it helps, works for you. I'm not surprised that it took so long for you to try a MAOI. Far to many combinations and various drug families to have to go through (mind you it took me 15 years) Take care, good health and wishes to you,pledge
This is the info I found on this site: ..Home › Drugs by Condition › D › Depression › Parnate Dosage
Generic name: tranylcypromine sulfate
Dosage form: tablet, film coated
This dosage information does not include all the information needed to use Parnate safely and effectively. See full prescribing information for Parnate.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Dosage and Administration for Parnate
Dosage should be adjusted to the requirements of the individual patient. Improvement should be seen within 48 hours to 3 weeks after starting therapy.
The usual effective dosage is 30 mg per day, usually given in divided doses. If there are no signs of improvement after a reasonable period (up to 2 weeks), then the dosage may be increased in 10 mg per day increments at intervals of 1 to 3 weeks; the dosage range may be extended to a maximum of 60 mg per day from the usual 30 mg per day.
Revised: 04/2011GlaxoSmithKline LLC
Amy Beth, please be careful with this MAOI it can have alot of interactions wiyh other meds, especially over the counter products. Research this med and also be sure to read ALL label precautions for ANY other medication you have to take, even non-prescription items. I wish you all the best in your treatment and I hope this info helps you! Lisa Z
- Parnate Information for Consumers
- Parnate Information for Healthcare Professionals (includes dosage details)
- Side Effects of Parnate (detailed)
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