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What is the Divalproe125mg and Divalproex ER 250mg and what is the difference?

Answers (1)

Anonymous 6 Sep 2010

Hello,

Depakote regular / Depakote ER.-

Valproate semisodium (INN) or divalproex sodium (USAN) consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form. It is used in the UK, Canada, and U.S. for the treatment of the manic episodes of bipolar disorder. In rare cases, it is also used as a treatment for major depressive disorder, and increasingly taken long-term for prevention of both manic and depressive phases of bipolar disorder, especially the rapid-cycling variant. It is also used in the US for the treatment of epilepsy, chronic pain associated with neuropathy, and migraine headaches. Its chemical name is sodium hydrogen bis(2-propylpentanoate). The extended release formulation allows for a single daily dose.

They are the same medication.-One is ER and the other is not.-

Dosage is based on your weight, medical condition, and response to therapy.

If you take 125 mgs I suppose you have to take 1 every 12 hours and the ER 250 just once daily please follow your doctor´s instructions.-

I take Depakene (valproic acid only) 500mgs, 250 am and 250mgs pm.- 1 every 12 hours.-

Take care.-

Plain Jane 6 Sep 2010

ER means Extended Release, made to last for longer periods of time, hense the tablet strength is usually stronger.

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