Ursodiol Dosage and Administration
General Dosing Information
The recommended adult dosage for Ursodiol tablets USP in the treatment of PBC is 13 to 15 mg/kg/day administered in two to four divided doses with food. Dosing regimen should be adjusted according to each patient's need at the discretion of the physician.
Hi - I don't think this will adequately answer your question but I wanted to share my short story about my experience with URSO and I hope will be useful.
I am 49 - I was just 30 when I was diagnosed with PBC back in Brisbane, Australia and although at that time I was symptom free, the disease was progressing at a relatively fast pace and was told that unless the progression was slowed, I would be facing a liver transplant before 40 years of age. I was immediately prescribed URSO and it was hoped that because I had been diagnosed at an early age, the drug would be beneficial.
The drug was somewhat successful but the progression was still at a rate that it seemed likely I would require liver transplantation at some time over the coming years.
I immigrated to the United States in early 2004 and immediately located a specialist in San Francisco to continue to monitor my disease. Now, this is what might be helpful to you - at my very first visit to my new doctor, he immediately doubed my dosage of URSO to 1500 mg per day. I am a larger woman (app 200 lb) and it was noted that my prior dosage was insufficient in comparison to my weight. My bloodwork and other tests immediately improved and the results have been nothing short of amazing. Although, this current situation may change at any time, it seems that the disease has been slowed considerably to a point where we are all cautiously optimistic that I may live the remainder of my life without requiring a liver transplant.
Again, I am sorry if this does not adequately answer your question but I am happy to share my story if it can help anyone who has PBC.
- Ursodiol Information for Consumers
- Ursodiol Information for Healthcare Professionals (includes dosage details)
- Side Effects of Ursodiol (detailed)
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