I have read that Depakote is used to treat migraines. I have ocular migraines (http://www.mayoclinic.com/health/ocular-migraine/AN01681/rss=1) and at one time was taking two pills a day which pretty much eliminated them. The liver must be checked periodically when on Depakote (either the liver or kidneys but I'm fairly certain it's the liver).
i take pristiq for depression 50 mg a day and then i take inderal not the LA kind but 80 mg am and 80 mg at bedtime, i also take topamax 300mg = 100mg in am and 200 mg at bedtime and i can truely say that it has been the best medication for ME i've been on the latter two meds for many years(15) appox. with very few migraines (depending on my stress level at home or work) i only started the pristiq in jan. of 09 with no side affects, when i started the inderal and topamax my doctor gave me a trigger migraine list, it told of foods and different things that could trigger a migaine maybe you have one or could ask you doctor for it ,maybe if they don't have one you could find it on the net. hope this has help you will be thinkig of you today.missy
One much less commonly used drug for both of these indications is Lamictal. It is originally an anti-seizure medicine similar to TopaMax, but in and of itself it is useful to combat unipolar depression.
To use, it is tapered up slowly to a maintenance dose, where you take it daily as a migraine and headache prophylactic -- and from my experience, its efficacy was what could be called no less than a wonder.
From daily, crippling pain to almost a full year with minimal migraine pain. If a lot of other options have failed you, speak with your prescribing physician about the possibility and benefits of using Lamictal.
I wish you the best in your future endeavours.
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