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What causes the side effect of goose bumps when taking phenylephrine?

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suzanne66 14 Nov 2009

Goose bumps are caused by a reflex called piloerection. Piloerection (goosebumps) occurs when the hair in the follicle lifts up and makes the hair follicle stand out. Goosebumps are caused by many emotions such as anger, fear, stress, excitement and arousal. Also by coldness and drug withdrawal.

In regards to phenylephrine I assume that you are referring to the nasal spray. In which case the reason you experience goosebumps is because of the "cold " feeling of the spray hitting your nasal mucosa. It is a common experience for many nasal spray users.

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