This is my 2nd question i have been diagnosed with seronegative ra and now fibromyalgia, been sick for 2 yrs an no improvement and the next step is biological drugs... Any info will help
Biologics are a new class of drugs that have been used since the late 90's and have been studied for almost 10 years. . A “biologic” drug copies the effects of substances naturally made by your body's immune system. These genetically engineered drugs are given to lessen inflammation by interfering with substances that cause or worsen inflammation.
They may be given when other medicines for rheumatoid arthritis have not worked. At times, your doctor will start biologic drugs sooner, along with other rheumatoid arthritis drugs.
Most of them are given either under the skin (subcutaneously) or into a vein (intravenously). There are different types of biologic agents:
White blood cell modulators include: abatacept (Orencia) and rituximab (Rituxan)
Tumor necrosis factor (TNF) inhibitors include: adalimumab (Humira), etanercept (Enbrel), infliximab (Remicade), golimumab (Simponi), and certolizumab (Cimzia)
Interleukin-6 (IL-6) inhibitors: tocilizumab (Actemra)
Biologic agents can be very helpful in treating rheumatoid arthritis. However, people taking these drugs must be watched very closely because of serious risk factors:
Infections from bacteria, viruses, and fungi
Leukemia or lymphoma
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