Have been prescribed Endep for 4 fold reasons. 1--chronic cluster headaches; hopefully to replace Topomax due to side effects. 2--migraine prevention. 3--nerve end pain (gynae related). 4 sadness following death of parent/insomnia/stress/depression and anything else you might like to throw in. Never been on it before. 64yo, pretty determined to get my life back on track, have had rough 12 months with extended periods in hospital with headaches etc. Any of you had any experience with any of my problems and Endep? Bit worried re side effects--especially weight as have just battled to get weight down after war with prednisolone. (the only bonus from Topomax was side effect of weight loss) Would I be better going to any of the other support groups? Your help would be appreciated? Thanks from South Australia!