Side Effects by Body System
Dermatologic side effects have been the most frequently reported and include local burning, crusting, allergic contact dermatitis, erosions, erythema, hyperpigmentation, irritation, pain, photosensitivity, pruritus, scarring, rash, soreness, and ulceration, and other local reactions.
The following side effects have been reported infrequently and a causal relationship is remote: alopecia, blistering, bullous pemphigoid, discomfort, ichthyosis, scaling, suppuration, swelling, telangiectasia, tenderness, urticaria, and skin rash.
One case of life-threatening systemic toxicity was associated with fluorouracil topical 5% cream in a patient with dihydropyrimidine dehydrogenase enzyme deficiency. Signs and symptoms included severe abdominal pain, bloody diarrhea, vomiting, fever, chills, stomatitis, erythematous rash, neutropenia, thrombocytopenia, and inflammation of the esophagus, stomach and small intestine.
Miscarriages and a birth defect (ventricular septal defect) have been reported when fluorouracil was applied to mucous membrane areas of pregnant women. A cleft lip and palate have been reported when fluorouracil was applied as recommended.
Hematologic side effects have included leukocytosis, which has been the most frequently reported hematologic side effect. Eosinophilia, thrombocytopenia, and toxic granulation have been reported infrequently and a causal relationship is remote.
Nervous system side effects have been reported infrequently and a causal relationship is remote. These included emotional upset, insomnia and irritability.
Gastrointestinal side effects have been reported rarely and a causal relationship is remote. These include medicinal taste and stomatitis.
Ocular side effects have been reported infrequently and a causal relationship is remote. These include conjunctival and corneal reactions, and lacrimation.
Nasal irritation has been reported infrequently and a causal relationship is remote.
Herpes simplex has been reported infrequently and a causal relationship is remote.
- Fluoroplex Information for Consumers
- Fluoroplex Information for Healthcare Professionals (includes dosage details)
- Side Effects of Fluoroplex (detailed)
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Hi just worrying about the side effects of ranatidine I have bad acid but I worry about side effect?
Posted 9 Dec 2010 • 1 answer