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What are the side effects of Cyclopentolate Hydrochloride Ophthalmic Solution?

Responses (1)

phillip6103 24 Sep 2009

Side/Adverse Effects

Note: An increased susceptibility to cyclopentolate and similar drugs (such as atropine) has been reported in infants, young children, children with blond hair or blue eyes, adults and children with Down's syndrome, children with brain damage or spastic paralysis, and the elderly. This susceptibility increases the potential for systemic side effects.

The following side/adverse effects have been selected on the basis of their potential clinical significance (possible signs and symptoms in parentheses where appropriate)—not necessarily inclusive:

Those indicating need for medical attention:

Symptoms of systemic absorption:

Ataxia (clumsiness or unsteadiness)

behavioral disturbances

psychotic reactions (unusual behavior, such as disorientation to time or place, failure to recognize people, hyperactivity, or restlessness, especially in children using 2% cyclopentolate)


diminished gastrointestinal mobility (constipation; full feeling or passing gas; stomach cramps or pain)

fast or irregular heartbeat



increased intraocular pressure


skin rash

slurred speech

swollen stomach—in infants

thirst or dryness of mouth

unusual drowsiness

tiredness or weakness

urinary retention(passing urine less often)

vasodilation (flushing or redness of face)

Those indicating need for medical attention only if they continue or are bothersome




punctate keratitis

synechiae(eye irritation not present before therapy)

blurred vision

burning of eye

photophobia(increased sensitivity of eyes to light)

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