What are the risks of taking promethazine hydrochloride with suboxone?
- Asked
- 11 Nov 2010 by BABY ANGEL
- Updated
- 11 Nov 2010
- Topics
- suboxone
Responses (1)
The risks reported are moderate on the Interactions checker, but would however recommend that you also discuss it with your doc who prescribed the meds.
Applies to: promethazine, Suboxone (buprenorphine/naloxone)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
https://www.drugs.com/interactions-check.php?drug_list=1949-0,439-2040

Further Information
- Suboxone Information for Consumers
- Suboxone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Suboxone (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Similar Questions
Promethazine with DM - I have been mistakently overdosing promethazine DM for the last 32 hours.?
Posted 30 Oct 2009 • 1 answer
Are there serious longterm health risks from suboxone? My life is at its best when I use opiates?
Posted 31 Jan 2010 • 3 answers
Promethazine VC Plain - hello all:) its been awhile since ive posted but I was just Rx'd?
Posted 17 Dec 2011 • 2 answers
Codeine/Promethazine - I've been taking 1 time daily at bedtime for over a year. Can this affect my
Posted 16 Oct 2014 • 1 answer
What is the brand name for promethazine hydrochloride?
Posted 1 Oct 2016 • 2 answers