It really depends on the medication and the amount of alcohol. It is generally not recommended as alcohol is a depressant and can increase the side effects of some medication causing things like decreased coordination, lack of good judgement and central nervous system and respiratory depression which means decreased heart rate and breathing. Because alcohol can increase the side effects of psychiatric medications and can increase depression, I recommend staying away from it.
If you would like to know the specific interaction potential, please list the medication and I would be happy to look it up.
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