... improvement so my doc is starting me on 300 XL I was under the impression that because it is 300 mg of XL that you take this all in one dose but on my Rx it says to take twice daily as once in the morning and once at night, I thought with the XL you take it all at once whether it is 150 or 300 because it is a extended release, anybody know the answer to this? Also wondering if anyone else has had to bump it up because of poor results and did this help. Also anyone experience acne problems with this, I seem to be getting more on my back that usual, does this go away in time, I also suffer from PMDD so this could be the culprit for that. Anyways anyone with experiences with Wellbutrin 300 mg XL please share, i could use all the feedback I can get