My doc prescribed me wellbutrin XL 150 mg ( generic). I have to take 1 in the morning and 1 at night. Today is the 6 day I have been taking it. Two days ago I had a burst of energy and felt so Happy and I was also talkative , but that was just for that 4th day. Now I have went back to being down and depressed. I am still taking it as directed and I am definitely going to give it 8 weeks before I fully Judge the medicine. My question is what happen to you when wellbutrin kicked in? Did you just wake up happy one day? Please let me know your experience with how long it took to kick in and how did you know it kicked in?