I have been chronically tired at all hours of the day for over 5 years. 9 months ago I was diagnosed with depression/anxiety. In addition to prestiq my doctor put me on 150mg wellbutrin twice a day. I have been taking it for almost a month. I don't feel any change in my tiredness and lack of motivation. He said it would be like 10 cups of coffee, I feel nothing. How long should I wait to see if it works? This tiredness is severely affecting my life and everyone else's.