I started taking glucophage xr 1000 mg twice a day from 2 weeks ago after being diagnosed with insulin resistance . I have irregular period,I'm overweight (BMI = 25.78) and I have acne . I took isosupra lidose 16mg twice and each time for 6 months and the acne reappears after one year of treatment . I was never diagnosed with PCOS.
I'm afraid the weight loss is a small amount, but more studies done well are needed. You're amount of glucophage may increase these numbers. Here they are from 2 different groups over 6 months' time:
12.8 lbs. + or - 15.4 lbs
6.39 lbs. to 19.8 lbs
I know that this is an old topic, but I thought I'd give my personal experience, having been on that dose for ~14 years.
In my experience, the medication helped to keep my fasting insulin level under 12, which is the normal healthy range. If I don't take it, I shoot up into the 40s (and when I was first diagnosed I was close to 280 and they didn't know how my pancreas was still working/I wasn't in a coma).
So, with that being said, the medicine does not "take weight off" of me. It MIGHT help me maintain/keep my weight from shooting up when I just eat normally (when before, I could look at food and balloon up). In order to LOSE, I have to play a specific role in making that happen. Meaning, I have to do something with intention - like eat under 1,500 calories per day, or repetitively exercise multiple times per week. I believe the med THEN helps my body to say "Okay, it's safe to let this weight go", and I have done things like successfully lose 80 pounds, which had been rapid-gained due to a medication before we found the culprit (it's now on my "medication allergy" list). LOL
So since this post is pretty old, how did you end up doing on it?
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