... arthritis in my lower back and when I started taking warfarin, it seemed to ease the discomfort in my lower back. Now that I am not taking it, it seems that my back pain from arthritis has reappeared and is worse than before I started taking warfarin. Not much discomfort when up and mobile during the day, but at night when I lay down to sleep, the pain is unbearable. I have tried Alleve and many other meds but have found no relief. My question is: Is this normal and if so then what might be my course of action be? Any advice would be greatly appreciated