I just changed from Celexa to Vortioxetine. I am into my 2nd week with the new meds. Today I have been less annoyed at everything so I am hopeful but after being on so many different meds still have my doubts. Doctor just added a new med for to take (don't know the name right now) with the V. I have been labeled as bipolar/mood disorder and cannot not function without proper meds.