After many surgeries and diagnosis of IBD, Chrohns, Ulcerative Colitis and intestinal adhesions... I still have extreme pain, diarrhea, and a hard time sleeping... I told my doctor that I may be depressed as I don't or can't leave my home and I feel totally joyless. He suggested vilazodone and I have a months supply which I haven't started yet because of many of the side effects reported indicate that taking this prescription describe the initial reason I seem to have become depressed about... let me also say that I've never taken anything like this before and prior to me disease(s) had a great passion for life and love!