I have been taking Venlafaxine 375 mg for sometime but recently it has become ineffective at keeping my depression at bay. My doctor lowered my dose to 300 mg and added Mirtazipine 30mg. Whilst I feel alot better I have put on 7 lb in 4 weeks (even though following a strict Slimming World diet, as my doctor had warned me of an increase in weight). Unfortunately, I can't afford to put on this weight as I am now 14st 4lb and 5 ft 5". Has anyone tried any other combinations with Venlafaxine. I would like to try Venlafaxine with wellbutin if possible. Any ideas??