I'm a 65yr old male with a history of hypogonadism due to blunt trauma to testicles in a fall. I also am on testosterone replacement therapy self injecting 1ml into thigh every 14 days. Can megestrol actually help with severe hot flashes, and if so how long would it typically take to note improvement?
The reason you were prescribed megestrol is an off-label use and there's no information about this from the manufacturer. I checked another site and only testosterone replacement therapy was used. I can't tell you how soon it will work. There are 3 reviews from people who used it for hot flashes at this link below:
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