... urologist, and he said my ph was low so he put me on potassium citrate three times a day, then it started hurting to urinate, so I called and after two different labs losing three urine cultures, my doctor decided to put me on macrodantin 100 mg 4x day. How long should it take to help if it is an infection? I am on day two this evening, and although the burning is gone, the cinch off you feel when your done going is still there and feels pressurized. Should I be concerned that it still feels that way? Could a stone they didnt see be stuck? how long does it take for the meds to work efficiently.?