I was so horribly sick, and the doctor's office said they wanted me to try it again for another week. Um... I could barely work due to the nausea and pain. I did NOT try it for another week. But I certainly need something to help with my blood sugars. I take Metformin ER as well as Lantus 48 units 2x a day (total of 96 units). I sit at a desk all day, so not much exercise, and live in the very cold state of Michigan. Any suggestion would be appreciated. Thanks. StarGlitter