... and sent home with 5 days of two 20 mg pills. I started my period that same day. Well, 5 days of antibiotics and the prednisone still I wasn't better so I went to the ER yesterday morning. Another shot of prednisone and another 5 days of the oral prednisone, an IV of antibiotics, and another 7 days of oral antibiotics. I am a mess!! I am crying, feeling useless, needy, anxious, and just plain feeling sorry for myself. Is this the prednisone side effects? Is it a double whammy PMS and the prednisone? All I know is that my poor husband is getting the worst of this I think. Any suggestions??