I need a definitive answer please. I am taking Truvada and Isentress 10 days in for a possible HIV exposure. I had 1 margarita at dinner with my Truvada for the holidays. My liver tests came back fine so I thought it was OK . Now read online and it says that alcohol may interfere with the drugs effectiveness and now I am freaking out. Also, will Advil, Lunesta or Xanax Interfere with the effectiveness or absorption of Truvada or Isentress. My doctor did not say anything Please let me know the facts please if you know for sure