I have severe osteoarthritis in my entire body since I was about 10. Just within the past 2 weeks my hands started swelling, hurting pretty bad, and my left hand the knuckles on my fingers have started sticking. Nothing much is working. Excedrin has helped some, but no aleve, no Motrin... does anyone use it on their hands and how much relief do you get? Has anyone tried it for diabetic neuropathy in your feet? And do the brand names make a difference when the active ingredient is the same? Thanks