... night. She seems to have a sleep seizure every 3-4 months. I am apprehensive about doing this because of the side effects. She has never had anti- seizure medication before, and I don't know whether having a occasional seizures warrants this. She only has seizures during stressful times during school time. She is 10 years old. Any thoughts, advice?
Hi, this is the dosage information for using Trileptal in chldren under 16 years of age, i am including it mainly as it appears to be a treatment that is used not just on the odd occasion, and is used twice daily rather than once in the evening... I would never disregard your doctors instructions(!), but you may be interested in this following transcript:
Adjunctive Therapy for Pediatric Patients (Aged 2-16 Years)
In pediatric patients aged 4-16 years, treatment should be initiated at a daily dose of 8-10 mg/kg generally not to exceed 600 mg/day, given in a twice-a-day regimen. The target maintenance dose of Trileptal should be achieved over two weeks, and is dependent upon patient weight, according to the following chart:
20-29 kg - 900 mg/day
29.1-39 kg - 1200 mg/day
>39 kg - 1800 mg/day
In the clinical trial, in which the intention was to reach these target doses, the median daily dose was 31 mg/kg with a range of 6-51 mg/kg.
In pediatric patients aged 2-<4 years, treatment should also be initiated at a daily dose of 8-10 mg/kg generally not to exceed 600 mg/day, given in a twice-a-day regimen. For patients under 20 kg, a starting dose of 16-20 mg/kg may be considered [see Clinical Pharmacology (12.3)]. The maximum maintenance dose of Trileptal should be achieved over 2-4 weeks and should not exceed 60 mg/kg/day in a twice-a-day regimen.
In the clinical trial in pediatric patients (2 to 4 years of age) in which the intention was to reach the target dose of 60 mg/kg/day, 50% of patients reached a final dose of at least 55 mg/kg/day.
Under adjunctive therapy (with and without enzyme-inducing AEDs), when normalized by body weight, apparent clearance (L/hr/kg) decreased when age increased such that children 2 to <4 years of age may require up to twice the oxcarbazepine dose per body weight compared to adults; and children 4 to ≤12 years of age may require a 50% higher oxcarbazepine dose per body weight compared to adults.
Side effect symptoms that have been reported are as follow: https://www.drugs.com/sfx/trileptal-side-effects.html, However is it very unlikely to suffer more than a few, if any of these symptoms. Please speak with your daughters doctor about anything that concerns you!
I would want to start her on it before the trip. She might be sleepy from it at first. What kind of trip is it, a family one, by herself at a camp for kids, or with someone else. You have to consider that most camps don't have a doctor and the camp isn't in the middle of town.
- Trileptal Information for Consumers
- Trileptal Information for Healthcare Professionals (includes dosage details)
- Side Effects of Trileptal (detailed)
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