I'm on Clindamycin Gel, Tretinoin Cream, and Doxycycline Mono (oral). I've been on the medications 3 weeks and I haven't seen much improvement.

I know that popping the cystic pimples (big whiteheads) can irritate the pimple and the skin around it but I was wondering if there's any way to pop them (while on the medicine) that limits the irritation? It's very hard for me to leave the big, nasty whiteheads.

I've read that you're supposed to apply the Clind and Tret to the entire face, but I only get the big and problematic pimples on my chin and around my mouth. My cheeks, nose and forehead are relatively clear. Should I continue to only apply the Clind and Tret on my problem area (around mouth) or should I also apply to the areas that are clear?