Oral submucous fibrosis is a chronic, progressive, irreversible, pre-cancerous and yet avoidable disorder of the mouth caused by chewing areca nut in betel quid or its variants.
The betel quid chewing habit must cease to minimize disease progression.
No treatment has been shown to be effective in reversing this condition.
The usual treatment is corticosteroid injections into the fibrotic bands every week for 6-8 weeks. Hyaluronidase, an enzyme to breakdown connective tissue, may be mixed with the cortisone. Mouth opening excercises are advised. Nutritional supplements may be added.
Surgery may be required for advanced disease to allow the mouth to open sufficiently for normal function.
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