I was wondering if it can be taken during the day, in smaller doses. I suffer from SEVERE anxiety. I am also taking Celexa. I have read this is not a good combination. Is this true.
Ho, Buddy! The regular formulation of trazadone releases the full dosage at once, whereas the extended release formulation releases smaller amounts throughtout the day.
Taking trazadone with Celexa (and many different combinations of drugs that affect serotonin) runs a slight risk of serotonin syndrome which can range from a mild illness to life-threatening. The incidence is rare and doctors commonly prescribe these combinations, but it is something you should be aware of, and a very good reason to always work closely with your doctor.
*One postmarketing surveillance study identified an incidence of 0.4 cases per 1000 patient-months. Additionally, around 14 to 16 percent of persons who overdose on SSRIs are thought to develop serotonin syndrome.
I have been taking 200-300 mg trazodone for many years and at the beginning of starting until just recent my psych doctor told me to take one 100 mg in the day if needed. You should be alright; however, you should talk to your doctor about it as we are all different.
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