from tramadol 50mg every 6 hrs. to nucynta er 50mg every 12 hrs. I am to started the new med. tomorrow morning, I'm worried about withdraws, she said I shouldn't have any problems from going to nucynta er from tramadol. I started taking tramadol the middle of Aug. 2013 4 tabs daily. for nerve damage pain. Found out it is CRPS/2 .