The elimination half life of tramadol is 6.3 hour for tramadol immediate-release and 7.4 hours for the metabolite. The t ½ is 7.9 hours for tramadol ER and 8.8 hours for the metabolite.
It takes approximately 5.5 x elimination half life's for a medicine to be cleared from your system, so if we take the maximum half life as 8.8 hours, then it'll take about 48.4 hours for it to be cleared. Therefore it'll be in the system for that long.
- Tramadol Information for Consumers
- Tramadol Information for Healthcare Professionals (includes dosage details)
- Side Effects of Tramadol (detailed)
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