The rash and itching occurred one to two hours after taking Pepcid C. Had been asleep but woke up with severe itching on arms and hands. It is now approx. 12 hours later and rash and itching have subsided. Even my earlobes were swollen! This seems to have been a severe allergic reaction to something. Had taken 2 aspirin after dinner, which may have been cause of heartburn. Am 84 years old, and heartburn is something I've had less than 15 times in my entire lifetime, so very unusual for me. Could Pepcid C cause it?