Skip to Content

Was told tramadol and effexor aren't safe to take together? True or false?

Responses (3)

WildcatVet 9 Oct 2015

Hi, Rainbow! You can and millions of people do but you need to be closely supervised for an extremely rare condition known as serotonin syndrome. Doctors are well aware of this and tailor drug dosages to the lowest effective and safe doses.
*Talk to your doctor before using traMADol together with venlafaxine. Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremor, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. Using traMADol with venlafaxine may also increase the risk of seizures not related to the serotonin syndrome.

Votes: +1
WildcatVet 9 Oct 2015

PS, I've taken then together for over 6 years with no ill effects.

Delila 10 Oct 2015

Hi, just to follow up on WCV's answer, i also took Tramadol with antidepressants for a long time with no ill effect. Obviously you need to take heed in the warning WCV gave you about Serotonin syndrome, be aware of the symptoms, and if you start to experience any please see your doctor right away!

Votes: +1
kjmcvay123 11 Oct 2015

Thesent 2 should not be taken together at least for me and dol made me have reactions free discount card

Further Information

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.

Similar Questions