I have been taking Tikosyn five or six years. I am also on Metoprolol, Jantoven, and Lisinopril. My EP says that Tikosyn is causing loss of kidney function. He wants me to get an ICD so I can get off Tikosyn. I have never read comments from other users of Tikosyn that they have kidney problems, and I don't know how the EP knows that Tikosyn is the cause.