... in a severe seizure disorder and showing psychotic behaviors? And the results of using antipsychotic med? My nephew is 22 yr old male with severe chromosome disorder resulting in severe seizure disorder. He has been on several antipsychotic meds to treat very disruptive behaviors. Is there a problem with mixing seizure meds and Thorazine? He does not respond favorably to Respirdol or Klonopin (excuse the spelling).