I am very depressed and anxious and I have had a panic attack in the 10 days since I took 100 mg of prednisone over 2 days and 125 mg of solu medrol through IV for a rash. I just want to feel better and the depression and worry feels like it is worsening. Is this normal? If so when will it wear off? Also I applied a topical steroid on myself as well and I have been taking some Xanax.