I had mild symptoms that gradually got worse over a couple weeks. Started between my two outer toes on right foot then it spread to the between the next toes and is now between all toes, left and right foot except for big toe and the next toe. Dr. prescribed terbinafine and after a week of use the dry/flaking skin was clearing up and itchiness was going away. That was 4 days ago, now the itchiness is back and skin is flaking again. I started taking antibiotics around that time but that shouldn't effect a topical cream treatment. If it keeps getting worse I think I'll go back to the Dr. this week.