No it shouldn't. I am on random Urine drug screen tests through my Methadone clinic and have been for the last 12 years, and I last year I was given Tamifu and it just happened that the very next day I was up for a urine test and it was totally clean. But you may want to check with the lab that processes your test or whoever you are getting the test through.
Hope this helps.
Good luck to ya!
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